Fenugreek is one of the oldest plants used in traditional medicine. It has been used for a long time due to its beneficial properties in the treatment of wounds, abscesses, arthritis, bronchitis, and digestive disorders [1]. The seeds are the most important and useful part of the fenugreek plant [1]. Many of the functional and medicinal properties of fenugreek are attributed to its chemical composition (20–25% protein, 45–50% dietary fiber, 20–25% mucilaginous soluble fiber, 6–8% fatty acids and essential oils, and 2–5% steroidal saponins) [2].   References 1. Meghwal M., Goswami T.K. A Review on the functional properties, nutritional content, medicinal utilization and potential application of fenugreek. J. Food Process. Technol. 2012;3:181–190. doi: 10.4172/2157-7110.1000181. [CrossRef] [Google Scholar] 2. Khorshidian N., Asli M.Y., Arab M., Mirzaie A.A., Mortazavian A.M. Fenugreek: Potential applications as a functional food and nutraceutical. Nutr. Food Sci. Res. 2016;3:5–16. doi: 10.18869/acadpub.nfsr.3.1.5. [CrossRef] [Google Scholar]

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Goldenseal (Hydrastis canadensis), a perennial herb member to the buttercup (Ranunculaceae) family. Goldenseal is native to Canada (Quebec, Canada), and Eastern United States, (Ohio River Valley, West Virginia, the mountains of North and South Carolina, Kentucky, Tennessee, and north New England and Upstate New York). Native Americans have traditionally used Goldenseal (Root & Rhizomes) extensively, for skin disorders, ulcers, fevers, internal inflammatory conditions, canker sores and stomach issues. Wild living Goldenseal has been considered as endangered due to overharvesting. Regardless of Goldenseal being rare in the wild, it is commercially grown in abundance.   The key constituents of Goldenseal found in the Root & Rhizomes of the plant are the Isoquinoline Alkaloids (Protoberberines): Berberine, Hydrastine, Berberastine, Hydrastinine, Canadine, Canalidine, Phytosterin, Albumin, Chlorogenic acid, Potassium. These Isoquinoline Alkaloids are found to have antibacterial and anti-inflammatory properties. Goldenseal has shown to work synergistically when taken with supplemental Berberine, to have a more pronounced anti-viral effect and enhance its antibacterial activity. Providing Immune support [1,2]. Goldenseal contains the naturally occurring Isoquinoline Alkaloid, Berberine. Berberine is well known for its various benefits and uses. Benefits of Berberine in Goldenseal have been shown to aid in regulating cholesterol levels, regulation & lowering of blood sugar/glucose levels, lowering blood pressure, and preventing E. Coli from binding to Urinary Tract walls, which may be helpful in Urinary Tract Infections (UTIs) [3].  Goldenseal is commonly combined with Echinacea to provide synergistic immune support. Goldenseal has been found to be helpful in digestive disorders, by soothing inflammation in the digestive tract, soothing acidity related to heartburn & acid reflux, which may help with ulcers. Anti-bacterial properties of Goldenseal have also been used help reduce gas & bloating from bad bacteria in the gut.   Suggested Use: Take 1 cap, 1-3 times per day or more often when in need, or as directed by a health care professional. References 1. Cecil CE, Davis JM, Cech NB, Laster SM. Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). Int Immunopharmacol. 2011 Nov;11(11):1706-14. doi: 10.1016/j.intimp.2011.06.002. Epub 2011 Jun 16. PMID: 21683808. 2. Ettefagh KA, Burns JT, Junio HA, Kaatz GW, Cech NB. Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition. Planta Med. 2011 May;77(8):835-40. doi: 10.1055/s-0030-1250606. Epub 2010 Dec 14. PMID: 21157683; PMCID: PMC3100400. 3. Abidi P, Chen W, Kraemer FB, Li H, Liu J. The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms. J Lipid Res. 2006 Oct;47(10):2134-47. doi: 10.1194/jlr.M600195-JLR200. Epub 2006 Aug 2. PMID: 16885565. LABEL

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Product Color: Green Wildcrafted in the USA NOW® Goldenseal Root is derived from the root of the Hydrastis canadensis plant. It has been used traditionally by Native Americans for hundreds of years and is still used by modern herbalists today. Natural color variation may occur in this product. Supplement Facts: Supplement Facts Serving Size: 2 Veg Capsules Servings Per Container: 25 Description Amount per Serving % Daily Value Total Carbohydrate <1 g <1%* Goldenseal Root(Hydrastis canadensis) 1 g (1,000 mg) †Daily Value not established. *Percent Daily Values are based on a 2,000 calorie diet. †Daily Value not established. Other Ingredients: Hypromellose (cellulose capsule) and Stearic Acid (vegetable source). Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens. Caution: For adults only. Consult physician if taking medication or have a medical condition. Continuous high level consumption of this product for more than 2 weeks of each month is not recommended. Not recommended for use by pregnant or nursing women. Keep out of reach of children. Natural color variation may occur in this product. Made and quality tested in the USA with globally sourced ingredients. Store in a cool, dry place after opening. Family owned since 1968. Suggested Usage and Caution: Take 2 capsules daily as needed. Store in a cool, dry place after opening. For adults only. Consult physician if taking medication or have a medical condition. Continuous high level consumption of this product for more than 2 weeks of each month is not recommended. Not recommended for use by pregnant or nursing women. Keep out of reach of children.  

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AlchePharma presents an innovative formula with some of the best natural antifungals available, with the added absorptive properties of DMSO ( Dimethylsulfoxide ).  

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• Helps to naturally keep histamine reactions in check.*• Balanced formula to support comfortable living year-round, indoors and outdoors.*• Reclaim your life!* Helps to support the body's normal immune response all year long. Contains beneficial plant derived flavonols and antioxidants to support histamine balance.* Ingredients: (per serving):Proprietary Blend 505 mgLobelia (whole plant) †Lemon balm (herb top) †Holy basil (leaf) †Perilla (seed) †Sage (leaf) †Rosemary (leaf)†† Daily Value Not established. Other Ingredients: Peppermint leaf extract, quercetin, hypromellose, microcrystalline cellulose, magnesium stearate. Suggested Use: Adults: Take 1 capsule, twice daily with water.After results have been attained, take 1 capsule daily for maintenance as required.

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Orzax Immune Defense provides a powerful blend of 9 carefully selected key ingredients to support your immune system and provide an antioxidant effect. Strong antioxidants like vitamin C may aid to strengthen the body’s defense mechanisms by protecting cells from potentially harmful molecules known as free radicals. * Almost all of the body’s organs and processes, including the immune system, depend on vitamin D.* Zinc is vital for the immune system’s function.* Quercetin belongs to the flavonoids class of plant chemicals and they act as antioxidants within the body.* Echinacea is loaded with compounds that function as antioxidants.* Elderberry includes antioxidants and vitamins to help the immune system.* The most significant oil of ginger, gingerol, has potent anti-inflammatory and antioxidant properties.* Beta-glucans function as immunomodulator agents, which means they set off a series of actions that control and enhance the immune system.* Turmeric possesses antioxidant, anti-inflammatory, and anti-microbial effects.* Additionally, it contains curcumin, which supports immune health by assisting your body in self-defense and functioning to the fullest extent possible.* Orzax Immune Defense provides a powerful blend of 9 carefully selected key ingredients to support your immune system and provide an antioxidant effect.* Ingredients: Elderberrry, Quercetin, Vitamin D, Zinc, Vitamin C, Echinacea, Ginger, Turmeric, Beta Glucan. Suggested Usage: As a dietary supplement for adults, take two (2) capsules daily.  

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Product Color: Brown w/Speckles Veterinarian Recommended Improved Flavor! NOW® Pets Immune Support is designed to help support your pet's immune system and innate resistance to pathogens, as well as help to enhance liver and kidney function. NOW® Pets Immune Support is made with natural botanicals and has been formulated by renowned veterinarian Dr. Barbara Royal, DVM, CVA, founder of the Royal Treatment Veterinary Center. For use in Dogs and Cats only. For added support take with NOW® Pets Omega-3 Support. Product Facts: Product FactsActive Ingredients per Chewable Tablet (1.05 g) Serving Size: See directions of use in suggested usage Servings Per Container: Varies depending on animal weight Description Amount per Serving % Daily Value Organic Mushroom Blend. A proprietary blend of [Trametes versicolor (Turkey Tail), Agaricus blazei (Sun Mushroom), Grifola frondosa (Maitake), Bionectria ochroleuca (Cordyceps sinensis Mushroom), Phellinus linteus, Hericium erinaceus (Lion’s Mane), Ganoderma lucidum (Reishi) and Lentinula edodes (Shiitake)] 125 mg Milk Thistle Extract 25 mg Turmeric Root Extract 25 mg Burdock Root 25 mg Licorice Root 25 mg Red Clover 25 mg Ashwagandha Root Extract 25 mg Selenium (from Selenium Amino Acid Complex) 25 mcg Other Ingredients: Calcium Carbonate, Cellulose, Cooked Fish Powder (pollock, pacific whiting, cod, hake), Silica, Stearic Acid, Tuna Flavor. Caution: Safe use in pregnant animals or animals intended for breeding has not been proven. Use with caution in animals on steroids. Long-term use may cause or contribute to water retention, hypertension and other cortisone-like side effects. If animal's condition worsens or does not improve, stop product administration and consult your veterinarian. Warnings: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately. Suggested Usage: Directions for Use:Up to 20 lbs. 1 tablet twice daily21 to 40 lbs. 2 tablets twice daily41 to 80 lbs. 3 tablets twice dailyOver 81 lbs. 4 tablets twice daily

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Background: There are many factors that can challenge a healthy immune system including, stress, exposure to toxic compounds, allergies, bacteria, viruses, irregular sleeping patterns and a poor diet. The immune system is very complicated and is comprised of many highly specialized immune cells, each of which play various roles in maintaining and regulating normal, healthy immune function. Immune Support is a comprehensive formula which provides essential vitamins and minerals for general nutritional support, and a generous supply of specialty agents specifically implicated in immune wellness.* The synergistic combination of ingredients in Immune Support helps provide an ideal environment for optimal immune function.* Features: Provides European standardized herbs, which are the most clinically studied botanicals on the market today. Featuring European standardized echinacea and astragalus extract. Standardized European echinacea extract has been clinically studied since the early 20th century. Premium mushroom extracts not found in other immune formulas including, Maitake Mushroom (TD fraction), Shitake and Reishi Mushroom. L- OptiZinc® is the most clinically studied form of zinc available and is the only patented form of methionine-bound zinc. Vitamins A, C, B-6, Folic Acid, B-12 and Pantothenic Acid. Benefits: Echinacea helps “activate” the immune system and stimulate certain immune cells that are critical to maintaining overall health.* Echinacea helps keep the respiratory system healthy when challenged, particularly during winter months.* Maitake, shiitake and reishi mushrooms all contain polysaccharide compounds that effectively stimulate important immune cells.* L-OptiZinc® a patented form of the essential trace mineral required for proper growth and function of many types of immune cells. It is also critical to the health of the thymus gland; location where immune cells known as T-cells are made.* Quercetin is a strong antioxidant and helps provide support for healthy levels of histamine; a chemical involved in cold and allergy-related symptoms.* Goldenseal contains the immunostimulatory compound berberine and garlic’s sulfur-containing compounds both provide added immune support.* Ligustrum is used in Traditional Chinese Medicine in supporting a healthy immune system.* Supplement Facts

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Indigenous to North America, Echinacea is one of the most well-studied plants in herbalism. Combined with licorice root and the celebrated elderflower and elderberry, this tea will give your immune system a boost when you need it most. And with sweet and tart elderberry notes mixed with warming cinnamon, this tea is as tasty as it is comforting. Cozy up with this tea and be ready for whatever comes your way! HERBAL POWER: This blend supports immune function with the power of echinacea and elderberry TASTE: Sweet, slightly tart berry notes with warming cinnamon PERSONALITY: Dependable, resilient and sure CAFFEINE LEVEL: Caffeine Free Ingredients: Organic Echinacea purpurea herb, organic cinnamon bark, organic licorice root, organic hibiscus flower, organic European elder dry fruit dry concentrate, organic European elder flower, organic Echinacea purpurea root extract (2-8:1) Suggested Usage: Pour 8 oz. freshly boiled water over 1 tea bag. Cover & Steep for 10-15 min. Squeeze & REMOVE tea bag to ensure maximum goodness. Enjoy 2 cups per day. Especially good with honey.  

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Life can be busy and sometimes our bodies need some extra support, including our immune system. That’s why our herbalists formulated this immune boosting tea with the echinacea plant that’s been traditionally used for generations to naturally stimulate the immune system.* It’s combined with bright lemon and ginger spice for a tasty blend that awakens your senses. Keep this immunity booster on-hand so you can make the most of your day. HERBAL POWER: This blend supports immune function with the power of echinacea TASTE: Bright and sweet, balanced with mild spice PERSONALITY: Fiery, smart and self-confident CAFFEINE LEVEL: Caffeine Free   Ingredients:  Organic ginger rhizome, Organic Echinacea purpurea herb, Organic lemon myrtle leaf, Organic lemon peel, Organic licorice root, Organic cardamom seed, Organic Echinacea purpurea root dry extract (2-8:1), Organic licorice root dry aqueous extract (6:1) Suggested Usage:  Pour 8 oz. freshly boiled water over 1 tea bag. Cover & Steep for 10-15 min. Squeeze & REMOVE tea bag to ensure maximum goodness. Enjoy 2 cups per day. Especially good with honey.

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