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Priorty
The process of building and maintaining bone structure involves numerous biochemical and physiological processes. Osteoblasts and osteoclasts are the two primary types of bone cells involved in maintaining skeletal structure. Osteoblasts are responsible for bone mineralization (building new bone). Osteoclasts are responsible for secreting acid and enzymes that help dissolve “old” bone ti sue into calcium and other components, some of which may be reused by the body. The balance of building and breaking down bone involves a complex interplay between various nutrients, hormones, and other biochemicals. Our Hi-Potency Calcium/Magnesium formula is designed to provide the structural components, as well as help support some of the complex biochemical and physiological processes involved in building and maintaining a strong, healthy bone structure.†
Features
- Provides a 2:1 ratio of calcium to magnesium, two important nutrients essential for bone structure.
- Contains vitamin D3 essential for overall bone health.
- Provides the essential trace mineral boron for its synergistic effects.
- Betaine HCL helps create a low pH (acidic) environment.
Benefits
- Promotes bone growth, density, and strength.†
- Calcium has been approved by the FDA for the prevention of osteoporosis.†
- The combination of calcium citrate, carbonate, and amino acid chelate provides sources of calcium with good bioavailability.
- Magnesium citrate and amino acid chelate are both highly bioavailable forms of magnesium and magnesium oxide contain a very high level of elemental magnesium. All provide structural support for bone tissue and magnesium is a cofactor for many important biochemical processes in the body, including supporting vitamin D metabolism and function.†
- Boron is an essential trace mineral required for various hormonal process that impact bone health and helps support the functions of calcium, magnesium, and vitamin D.†
- Betaine hydrochloride is added for its ability to help contribute to a low pH (high acidity) environment which is conducive to calcium absorption.†
LABEL
We review the new research in regard to the phenomenal strength gains of post menopausal females who took Vitamin D for 9 months.
* Effect of vitamin D supplementation alone on muscle function in postmenopausal women: a randomized, double-blind, placebo-controlled clinical trial.
Osteoporosis Int. 2015 Oct;26(10):2413-21. doi: 10.1007/s00198-015-3151-9. Epub 2015 May 9
Those in the intervention group who took the supplements had a lower recurrence rate for vertigo episodes after an average of one year than those in the observation group. People taking supplements had an average recurrence rate of 0.83 times per person-year, compared to 1.10 times per person-year for those in the observation group, or a 24% reduction in the annual recurrence rate.
#vertigo #bppv #vitamind
Seong-Hae Jeong, Ji-Soo Kim, Hyo-Jung Kim, Jeong-Yoon Choi, Ja-Won Koo, Kwang-Dong Choi, Ji-Yun Park, Seung-Han Lee, Seo-Young Choi, Sun-Young Oh, Tae-Ho Yang, Jae Han Park, Ileok Jung, Soyeon Ahn, Sooyeon Kim. Prevention of Benign Paroxysmal Positional Vertigo with Vit D Supplementation: A Randomized Trial. Neurology, 2020; DOI: 10.1212/WNL.0000000000010343
Researchers witness a 10.4% reduction in arterial stiffness in just 16 weeks with high dose oral vitamin D.
Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial. PLOS ONE, 2017; 12 (12): e0188424 DOI: 10.1371/journal.pone.0188424
7,000 IUs/daily of Vitamin D needed claim researchers
- The recommended intake of vitamin D specified by the IOM is 600 IU/day through age 70 years, and 800 IU/day for older ages. "Calculations by us and other researchers have shown that these doses are only about one-tenth those needed to cut incidence of diseases related to vitamin D deficiency,"
- "We call for the NAS-IOM and all public health authorities concerned with transmitting accurate nutritional information to the public to designate, as the RDA, a value of approximately 7,000 IU/day from all sources."
* A Statistical Error in the Estimation of the Recommended Dietary Allowance for Vitamin D Nutrients 2014, 6(10), 4472-4475; doi:10.3390/nu6104472
High Vitamin D Levels associated with an 82% reduction in Breast Cancer Incidence
"We found that participants with blood levels of 25(OH)D that were above 60 ng/ml had one-fifth the risk of breast cancer compared to those with less than 20 ng/ml," said principal investigator and co-author Cedric F. Garland, DrPH, adjunct professor in the UC San Diego Department of Family Medicine and Public Health. Risk of cancer appeared to decline with greater levels of serum vitamin D.
Breast cancer risk markedly lower with serum 25-hydroxyvitamin D concentrations 60 vs 20 ng/ml (150 vs 50 nmol/L): Pooled analysis of two randomized trials and a prospective cohort McDonnell SL, Baggerly CA, French CB, Baggerly LL, Garland CF, et al. (2018) Breast cancer risk markedly lower with serum 25-hydroxyvitamin D concentrations 60 vs 20 ng/ml (150 vs 50 nmol/L): Pooled analysis of two randomized trials and a prospective cohort. PLOS ONE 13(6): e0199265.
A review published in The Journal of the American Osteopathic Association found Vitamin D can't be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50 percent of Americans
Citation: Role of Magnesium in Vitamin D Activation and Function, The Journal of the American Osteopathic Association, March 2018, Vol. 118, 181-189. doi:10.7556/jaoa.2018.037
Vitamin D reduces lung disease flare-ups by over 40 percent
- Patients with a vitamin D deficiency benefited dramatically from taking the supplements but the striking reduction in flare-ups was not seen among patients who had a higher vitamin D status at the start of the trial. However, researchers did find vitamin D supplementation modestly reduced the severity and duration of flare-up symptoms in all patients in the vitamin D group, regardless of their baseline vitamin D levels, compared to the placebo group.
* Published in the journal Lancet Respiratory Medicine DEC 2014
We review the the study "Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data" by the BMJ in regard to the amount of vitamin D needed to prevent colds and flu on a daily basis.
In conclusion, we found significant relationships between vitamin D levels and the number COVID–19 cases and especially the mortality caused by this infection. The most vulnerable group of population for COVID–19 is also the one that has the most deficit in Vitamin D
The role of Vitamin D in the prevention of Coronavirus Disease 2019 infection and mortality DOI:10.21203/rs.3.rs-21211/v1
We review the research " Association between vitamin D deficiency and heart failure risk in the elderly " in which they reported a 12.2 times increased risk of heart failure among those with low Vitamin D levels.
Vitamin D supplements protect against severe asthma attacks. We look at the meta-analysis conducted by the Lancet which showed the possible benefits of oral vitamin D supplementation reducing the likelihood of a severe asthma attack.
Citation: Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data DOI:10.1016/S2213-2600(17)30306-5
Study: Link between vitamin D and dementia risk confirmed
- The study found that people with low levels of vitamin D had a 53-percent increased risk of developing dementia and those who were severely deficient had a 125-percent increased risk compared to participants with normal levels of vitamin D.
People with lower levels of vitamin D were nearly 70 percent more likely to develop Alzheimer's disease and those who had severe deficiency were over 120 percent more likely to develop the disease.
* August 6, 2014, online issue of Neurology
We review the study " Widespread vitamin D deficiency likely due to sunscreen use, increase of chronic diseases, review finds " in regard to sunscreen being associated with mass vitamin D deficiencies.
Citation: Vitamin D Deficiency, Its Role in Health and Disease, and Current Supplementation Recommendations. The Journal of the American Osteopathic Association, 2017; 117 (5): 301 DOI: 10.7556/jaoa.2017.055
Omega-3 fatty acids, vitamin D may control brain serotonin, affecting behavior and psychiatric disorders
- Many clinical disorders, such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), bipolar disorder, schizophrenia, and depression share as a unifying attribute low brain serotonin. "In this paper we explain how serotonin is a critical modulator of executive function, impulse control, sensory gating, and pro-social behavior," says Dr. Patrick. "We link serotonin production and function to vitamin D and omega-3 fatty acids, suggesting one way these important micronutrients help the brain function and affect the way we behave."
- Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar, schizophrenia, and impulsive behavior Published online before print February 24, 2015, doi: 10.1096/fj.14-268342
We review the recent clinical study " Role of magnesium supplementation in the treatment of depression: A randomized clinical trial" in regard to the oral supplement of elemental magnesium. Citation: Role of magnesium supplementation in the treatment of depression: A randomized clinical trial DOI: 10.1371/journal.pone.0180067
Magnesium deficiency and pancreatic cancer We review the recent research " Magnesium intake may be beneficial in preventing pancreatic cancer " in which a lack of magnesium was inversely related to pancreatic cancer risk. * Magnesium intake and incidence of pancreatic cancer: the VITamins and Lifestyle studyBritish Journal of Cancer 113, 1615-1621 (1 December 2015) | doi:10.1038/bjc.2015.382
Magnesium deficiency and pancreatic cancer We review the recent research " Magnesium intake may be beneficial in preventing pancreatic cancer " in which a lack of magnesium was inversely related to pancreatic cancer risk. * Magnesium intake and incidence of pancreatic cancer: the VITamins and Lifestyle studyBritish Journal of Cancer 113, 1615-1621 (1 December 2015) | doi:10.1038/bjc.2015.382
We briefly review the study "Low serum magnesium levels are associated with increased risk of fractures: a long-term prospective cohort study" in regard to decreasing bone fracture risk by 44%. Citation: Low serum magnesium levels are associated with increased risk of fractures: a long-term prospective
* Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.