Vitamin E is the term used for the family of eight compounds that possess vitamin E activity. The eight compounds are alpha, beta, gamma, delta-tocopherol, and tocotrienol. Vitamin E represents the body’s major fat-soluble antioxidant. This means that it works effectively in parts of the body where lipids (fats) are located, such as the cell membrane, where it helps protect the fats in the membrane from free radical damage.†Protecting the cell membrane is critical for maintaining the overall health of all body cells. Vitamin E also helps support healthy immune and cardiovascular function.†All vitamin E from AlchePharma is natural vitamin E. Synthetic vitamin E is not the same as natural and has significantly less biological activity. While d-alpha is the most well-known and most researched member of the vitamin E “family”, gamma-tocopherol possesses unique characteristics that complement the biological effects of alpha-tocopherol. This formula contains a high amount of alpha-tocopherol along with smaller amounts of beta, gamma, and delta-tocopherol for a synergistic effect.†
Features
Also available as 200 IU and 400 IU.
Alpha-tocopherol is the most recognized form of vitamin E.
Beta, gamma and delta tocopherols are naturally occurring in our foods as part of the vitamin E complex and are included here for their synergistic effects.
Gamma-tocopherol has been and continues to be the focus of several research studies.
Benefits
Alpha-tocopherol has the ability to work in the body as a lipid-soluble antioxidant, helping neutralize already formed free radicals.†
Numerous research studies over the years have demonstrated the powerful antioxidant effects of alpha-tocopherol.†
Gamma-tocopherol helps support nitric oxide (NO) production; NO supports cardiovascular health.†
Alpha-tocopherol helps neutralize free radicals that have already formed and gamma-tocopherol inhibit the production of free radicals, these mechanisms demonstrate the synergy between these two forms of vitamin E.†
It is difficult to obtain the number of tocopherols needed to achieve optimal health through diet alone, therefore supplementation is important, as demonstrated by numerous published research studies.†
Scientists figure out how vitamin E keeps muscles healthy
Vitamin E has long known as a powerful antioxidant, and now scientists have shown that without it, the plasma membrane, which essentially keeps a cell from spilling its contents and controls what moves in and out, cannot properly heal.
The scientist suspects knowing the cell membrane repair action of vitamin E has implications for muscular dystrophy, and common diabetes-related muscle weakness, as well as traumatic brain injury, resulting from collisions on a football field, battlefield, or roadway. With a traumatic brain injury, for example, one of the first events that happens is that the plasma membrane of the neurons, key cells in the central nervous system, tear.
"Part of how we build muscle is a more natural tearing and repair process -- that is the no pain, no gain portion -- but if that repair doesn't occur, what you get is muscle cell death. If that occurs over a long period of time, what you get is muscle-wasting disease,"
"This means, for the first time, 83 years after its initial discovery, we know what the cellular function of vitamin E is, and knowing that cellular function, we can now ask whether we can apply that knowledge to medically relevant areas," McNeil said.
The antioxidant requirement for plasma membrane repair in skeletal muscle. Free Radical Biology and Medicine, 2015; 84: 246 DOI: 10.1016/j.freeradbiomed.2015.03.016
Vitamin E results in a 49% reduced risk of cardiovascular death
Optimal dose of vitamin E maximizes benefits, minimizes risk
* published in the November 2008 issue of Nutrition Reviews
- One of the most compelling studies of the benefits of vitamin E is the Women's Health Study, in which 40,000 healthy women, 45 and older, took 600 IU vitamin E supplements or a placebo every other day for 10 years. Women taking the supplements had 24 percent fewer deaths from heart disease. Vitamin E's protective effect appeared even stronger in women 65 and older. Those taking the vitamin experienced a 26 percent reduction in cardiovascular events and a 49 percent reduction in cardiovascular deaths.
Vitamin E intake critical during ‘the first 1,000 days’
**Watch in HD**
- “surveys show that 90 percent of men and 96 percent of women don’t consume the amount currently recommended”
* Published in Advances in Nutrition Sep 2014
Compared to the mice that had normal amounts of vitamin E in their diet, the mice fed extra vitamin E had:
1,000 times fewer bacteria in their lungs
Two times fewer the number of white blood cells (neutrophils)
The reduced numbers of bacteria and white blood cells resulted in less lung damage in the older mice who received extra vitamin E. These mice were able to control the infection as efficiently as young mice.
* Published online before print December 15, 2014, doi: 10.4049/jimmunol.1402401
Study results showed that lower levels of serum albumin and four dietary antioxidants - vitamins A, B2, E, and folate -- were associated with a higher risk of HR-HPV infection. Albumin is the most bountiful circulating protein in plasma, and decreased serum albumin was found to be associated with increased systemic inflammation and impaired immune response. Based on the four dietary antioxidants, the researchers developed a nutritional antioxidant score.
#HPV #Antioxidants #infection
Hui-Yi Lin, Qiufan Fu, Yu-Hsiang Kao, Tung-sung Tseng, Krzysztof Reiss, Jennifer E Cameron, Martin J Ronis, Joseph Su, Navya Nair, Hsiao-Man Chang, Michael E Hagensee, Antioxidants Associated with Oncogenic HPV Infection in women, The Journal of Infectious Diseases, 2021;, jiab148, https://doi.org/10.1093/infdis/jiab148
HPV, antioxidants, infection, vitamin a, riboflavin, vitamin e, folate, folic acid, dietary antioxidants, carcinogenesis, HR-HPV, serum albumin, cancer, plasma, oncogenic, NHNES, human papillomavirus
* Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
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