Optimizing B-Vitamin Utilization with Alchepharma's Coenzymated B-Complex: A Potential Intervention for Enhanced Energy and Wellbeing
Introduction: B vitamins are essential micronutrients involved in diverse biological processes, impacting energy production, neurological function, and general well-being. However, individual variations in absorption and conversion can limit their effectiveness. Here, we explore the scientific rationale behind Alchepharma's Coenzymated B-Complex, a novel formulation designed to overcome these limitations and deliver optimal B-vitamin benefits.
Challenges with Traditional B Vitamins: Traditional B vitamins require metabolic conversion before active utilization. This process can be hindered by genetic factors, particularly MTHFR polymorphisms, affecting approximately 30% of the population. Additionally, age-related declines in intrinsic factor can further compromise B12 absorption.
The Advantage of Methylated B Vitamins: Alchepharma's Coenzymated B-Complex leverages fully methylated B vitamins, bypassing the conversion step for significantly faster and more complete absorption. This approach holds particular promise for individuals with MTHFR variations or compromised absorption.
Beyond Essential B Vitamins: This formula transcends a basic B-complex by incorporating synergistic nutrients like Choline, Inositol, PABA, and Alpha Lipoic Acid. Choline and Inositol contribute to neurotransmitter synthesis and membrane health, while PABA supports folate metabolism. Alpha Lipoic Acid, a potent antioxidant, enhances B-vitamin activity and offers additional cellular protection.
Scientific Support for Methylated B Vitamins: Growing evidence suggests numerous benefits associated with methylated B vitamins, including:
Improved energy levels and reduced fatigue: Studies demonstrate enhanced cellular energy production and metabolic efficiency upon B-vitamin supplementation.
Enhanced cognitive function and memory: B vitamins play crucial roles in neurotransmitter synthesis and neuronal signaling, potentially improving cognitive performance and memory consolidation.
Elevated mood and reduced stress: B vitamins support the production of mood-regulating neurotransmitters like serotonin and dopamine, potentially contributing to emotional well-being and stress management.
Support for healthy homocysteine levels: Elevated homocysteine is a risk factor for cardiovascular disease. B vitamins, particularly B12 and folate, play a critical role in homocysteine metabolism, offering potential cardiovascular benefits.
Potential benefits for nerve function: B vitamins are essential for maintaining healthy nerve sheaths and supporting nerve signal transmission. Studies suggest potential benefits for neuropathy and nerve health maintenance.
Quality and Safety: Alchepharma's Coenzymated B-Complex adheres to rigorous quality standards, being vegan-friendly, gluten-free, and free of artificial ingredients. Furthermore, it is manufactured in a GMP-certified facility, ensuring safety and consistent quality.
Conclusion: Alchepharma's Coenzymated B-Complex offers a scientifically founded approach to B-vitamin supplementation, incorporating methylated forms for enhanced absorption and additional synergistic nutrients for comprehensive support. While individual needs may vary, this formula holds promise for individuals seeking to optimize their energy levels, cognitive function, and overall well-being, particularly those with MTHFR polymorphisms or compromised B-vitamin absorption. Consult your healthcare professional for personalized guidance before starting any new supplement regimen.
Disclaimer: This information is for educational purposes only and should not be interpreted as medical advice. Please consult your healthcare professional before making any changes to your supplement regimen.
Label
Certificate of Analysis
Background:
Male virility and sexual health depend upon several factors. Sex drive is influenced by thenormal, healthy production of hormones such as testosterone. Adequate hormone productionhelps drive the physiological processes involved in sexual health. The complex relationshipbetween hormones, enzymes and other biochemicals must be carefully nurtured if apsychological, physiological and anatomical balance that supports optimal sexual health can beattained. ViriloMax is a Male formula that has been synergized with an herbalblend to support the processes involved in promoting a healthy male sex drive, energy andstamina.*
Features:
Standardized horny goat weed extract (10% icariins).
Male formula with co-actors for libido enhancement*
Replete with the best known herbal male aphrodisiacs: Korean Ginseng, Maca, KolaNut, Muira Puama, Damiana, Fenugreek, and Tribulus.
All natural easy-to-swallow capsules
Benefits:
Active ingredient in horny goat weed, icariin has been shown to be an effective regulator of the PDE-5 enzyme. This enzyme is involved in blood vessel dilation and circulation, both of which are critical for male sexual health.*
Tribulus terrestris has been shown to support healthy testosterone levels.*
Maca helps promote endurance, energy, vitality and sexual virility.*
Korean Ginseng is a potent adaptogen that helps support energy and vitality.*
Damiana and Muira Puama are both potent aphrodisiacs and help support libido and male vitality.*
Ingredients
Lecithin is a natural emulsifier found in many foods. It is often found in foods such as mayonnaise (mixture of fat and water-soluble substance) where eggs which contain lecithin act as an emulsifying agent to keep them mixed together rather than separated such as what happens in a mixture of oil and vinegar due to a lack of an emulsifier like lecithin. Our lecithin is derived from soybeans. Lecithin from soy is an excellent source of phospholipids. These compounds play important structural and functional roles in the cell, particularly the cell membrane. About 60% of the dry weight of the brain is composed of phospholipids, hence their importance in brain structure and function. As part of the structure of brain cell membranes, phospholipids help support neurotransmitter and hormone function, as they provide the environment that cells need for cell to cell communication and overall cell function. Phosphatidylcholine is a good source of choline, which is needed to support neurotransmitter production, essential for the normal, healthy functioning of the nervous system. Lecithin has also been studied for its role in helping to support healthy cholesterol metabolism, fat digestion and metabolism, thereby providing support for healthy cholesterol levels.*
Benefits:
Excellent source of phosphatidylcholine (PC), an important phospholipid that is a significant component of the cell membrane particularly that of nerve cells including the brain.
PC is also a source of choline which is used by the body to make the important neurotransmitter acetylcholine.
Lecithin is also a source of other phospholipids including phosphatidylinositol and phosphatidylethanolamine. Both of these compounds are critical to normal, healthy cell function.*
Phosphatidylcholine provides a source of choline which the body uses to manufacture acetylcholine, a neurotransmitter involved in numerous neurological mechanisms including cell
to cell communication, particularly as it relates to learning and short term memory.*
PC levels have been shown to decline with age, therefore supplementation becomes even more important as we age.*
PC has also been shown to help support normal, healthy liver and gall bladder function.*
Background:
Ultra Proteo-Zimes™ is a systemic enzyme formulation that contains a unique blend of enzymes that have been clinically studied to support numerous biological processes.* These enzymes are designed to be digested and absorbed in the small intestine and travel directly to the blood and are therefore not designed to assist in the digestive process itself; with the exception of some support of protein digestion. Once absorbed these enzymes go to work helping to break down specific protein molecules that may be directly involved in inflammation, poor circulation, pain and stiffness.* The enzymes in Ultra Proteo-Zimes™ help support healthy cardiovascular, immune and joint function as well help support tissue repair.*
Features:
Very high potency systemic enzyme formula.
Compares to the leading systemic enzyme brand.
Contains the highest commercial concentrations available of: chymotrypsin trypsin, pancreatin, papain and bromelain.
Enteric–coated tablet prevents the destruction of the enzymes by stomach acid.
Gluten free
Benefits:
Systemic enzymes support healthy joints, particularly joint mobility, by ensuring a normal, healthy response to inflammation.*
Supports healthy circulation through its fibrinolytic action (breaks down fibrin which may cause excess blood clotting) within the cardiovascular system.*
Supports a healthy immune system by limiting the production of cytokines (molecules that cause inflammation).*
Helps support the breakdown of proteins in the intestinal tract thereby aiding in the digestion and absorption of proteins.*
Ingredients
There are natural ingredients that have been discovered to promote healthy testosterone levels and improve male sexual health. One of these ingredients is Tribulus terrestris which has shown promising results. Horny goat weed contains Icariin, an active ingredient that regulates the PDE-5 enzyme, which is important for blood vessel dilation and circulation in males. Yohimbe Bark Extract, which is standardized to 4% Yohimbine, inhibits Alpha-2 Adrenergic receptors and may positively affect neurotransmitters such as serotonin and dopamine, potentially improving vitality and mood. Maca and Korean Ginseng are both adaptogens that can help promote endurance, energy, and vitality. Lastly, Muira Puama is a potent aphrodisiac that can support male vitality.
Benefits:
Tribulus terrestris has been shown to support healthy testosterone levels.*
Active ingredient in horny goat weed, icariin has been shown to be an effective regulator of the PDE-5 enzyme. This enzyme is involved in blood vessel dilation and circulation, both of which are critical for male sexual health.*
Yohimbe Bark Extract, Standardized to 4% Yohimbine. Yohimbine is known for inhibition of Alpha-2 Adrenergic receptors, which may exhibit a benefit in Erectile Ability. Also may increase norepinephrine release, which may have a stimulant effect on Mood and Energy. Additional benefits may have a positive effect on Neurotransmitters, such as: Serotonin, Dopamine, and Cholingeric receptors, potentially postitive effect on Vitality.
Maca helps promote endurance, energy, vitality and sexual virility.*
Korean Ginseng is a potent adaptogen that helps support energy and vitality.*
Muira Puama can be a potent aphrodisiac and help support male vitality.*
Ingredients
Maximum Male™
Supplement FactsServing Size: 4 TabletsServings Per Container: 30Tribulus terrestris Fruit 600 mg *Maca Root (Lepidium meyenii) 300 mg *Yohimbe Bark Extract (Pausinystalia yohimba, standardized to 4% yohimbine) 230 mg *Muira Puama 4:1 Extract (Ptychopetalum olacoides root) 200 mg *Oat Straw 10:1 Extract (Avena sativa leaf) 200 mg *Sarsaparilla Root (Smilax medica) 200 mg *American Ginseng Root (Panax quinquefolius) 125 mg *Horny Goat Weed Herb Extract (Epimedium sagattatum) 100 mg *(standardized to 10% icariin)Korean Ginseng Root (Panax ginseng) 100 mg *Ginkgo biloba Leaf Extract 60 mg *(standardized to 24% ginkgoflavonglycosides and 6% triterpene lactones)Ginger Root (Zingiber officinale) 50 mg *Freeze Dried Oysters 20 mg *Eleutherococcus senticosus Root 50:1 Extract 5 mg *Other Ingredients: Cellulose, silica, magnesium stearate, vegetable stearate, and niacin (20% DV†).NO corn, soy, salt, yeast, wheat, milk & egg products, sugar, starch, or preservatives.Two tablets twice daily, with meals, as a dietary supplement.WARNING: Men with heart conditions or taking heart medication should consult with their health care practitioner before using any Yohimbine products. Contain shellfish (oysters).
Due to its strong adaptogenic properties, Ashwagandha Extract is often referred to as Indian Ginseng. It plays a central role in the practice of Ayurvedic medicine in India, where it is believed to help create and maintain vitality, energy, rejuvenation, and to avoid insomnia and other nervous conditions. The plant, scientifically designated as Withania somnifera, grows throughout India, the Middle East, and in parts of Africa. It contains steroidal lactones known as withanolides, which have been shown through scientific studies to be responsible for the health-promoting benefits of the plant.
Features
Standardized Ashwagandha Extract from Sabinsa, a world leader in Ayurvedic herbal extracts.
500mg per capsule, standardized to 2.5% Withanolides.
Standardized Ashwagandha Extract has been used in numerous clinical studies, continuously showing its effectiveness against inflammation for over 40 years.
Vegetarian Capsules, Vegan Friendly, Gluten Free, Dairy-Free.
Benefits
Helps maintain healthy cortisol levels.†
Helps reduce fatigue and improve energy.†
Acts as an adaptogen, helping to maintain the body’s healthy response to physiological and psychological stress.†
Helps maintain mental focus and acuity.†
Helps improve physical performance and strength.†
Helps maintain a positive outlook.†
Helps promote restful sleep.†
Helps maintain healthy blood sugar levels.†
Helps mitigate oxidative injury caused by nervous tension.†
Ingredients
Cordyceps (Cordyceps sinensis) mushrooms are different than many others in that they are parasitic fungi. They grow all over the world, infecting insects as their host. Cordyceps can be hard to source and/or expensive, so some cordyceps supplement manufacturers will now source a natural cordyceps that has been grown into a vegetarian or vegan substrate (often grain-based). Cordyceps might improve immunity by stimulating cells and specific chemicals in the immune system, and by supporting an increase in the number of red blood cells, which transport oxygen and carbon dioxide to and from tissue.† There are also studies that demonstrate the positive role of Cordyceps mushroom in cardiovascular function and glucose support.†
Features
2 Vegetarian Capsules providing 1g of Organic Cordyceps (Cordyceps sinensis) Mushroom Mycelium Powder
U.S. Grown
Standardized to 40% polysaccharides, 400 mg
Contains no: sugar, salt, dairy, wheat, gluten, peanuts, tree nuts, preservatives, artificial colors, or artificial flavors.
Gluten Free, Non GMO, and Vegan
Benefits
Cordyceps may boost VO2 Max, increasing how much oxygen the body has to use during exercise and physical labor.†
Cordyceps are thought to increase the body’s production of the molecule adenosine triphosphate (ATP), which is essential for delivering energy to the muscles.†
In traditional medicine, Cordyceps is believed to help with aging. The elderly have historically used Cordyceps to reduce fatigue, boost strength and restore sex drive.
Several studies suggest Cordyceps may support healthy blood sugar levels.†
Cordyceps may also have a beneficial effect on cholesterol levels. Animal research has shown that Cordyceps decrease “bad” LDL cholesterol and Triglycerides.†
Cordyceps is said to promote a healthy inflammatory response. Research has shown that when human cells are exposed to Cordyceps, special proteins that increase inflammation in the body may be suppressed.†
Cordyceps showed up in Tibetan medical transcripts way back in the 15th century, where it was used as an aphrodisiac. Today it is used for mood enhancement.†
LABEL
Leucine, Isoleucine and Valine are three essential amino acids with a unique branched-chain structure. The BCAAs are the only amino acids used by the mitochondria to produce energy (Haas & Mela-Riker). They comprise about one-third of the protein content of muscle tissue and are used preferentially by muscle tissue for energy production. Clean Fit™ BCAA’s are a balanced blend of Leucine, Isoleucine and Valine that’s synergized with Vitamins B1, B3, B5 and glutamine for enhanced utilization. It’s water-soluble, mixes easily in water and has a delicious natural watermelon flavor.
Features:
Free of hormones, steroids and artificial stimulants
Contains a 2:1:1 blend of the three branched chain amino acids: Leucine, Isoleucine and Valine
Micronized form is water-soluble for easy mixing
Delicious watermelon flavor
Optimized with glutamine, B1, B3 and B5
Gluten free
Benefits:
Provides the three branched chain amino acids that are used preferentially by skeletal muscle for energy. *
Provides leucine, which is completely oxidized for energy in muscle. *
Leucine promotes protein synthesis in skeletal muscle.*
Supplementation with BCAA’s has been shown to decrease exercise-induced muscle protein breakdown, increase protein synthesis and enhance post-exercise muscle recovery.*
When taken during training BCAA’s decrease muscle soreness and the sensation of fatigue.*
Vitamin B1, thiamin, may enhance circulation, helps with blood formation and the metabolism of carbohydrates.*
Vitamin B3, niacin, is required for cell respiration, helps in the release of energy and metabolism of carbohydrates, fats, and proteins, proper circulation and healthy skin, the functioning of the nervous system, and normal secretion of bile and stomach fluids.*
Vitamin B5, pantothenic acid, is used in the release of energy as well as the metabolism of fat, protein and carbohydrates.*
Glutamine is an amino acid that aids muscle growth by increasing levels of leucine in muscle fibers, inhibiting breakdown and encouraging muscles to store more glycogen, which makes them fuller due to the water that glycogen holds. It also is an anti-catabolic agent.*
Label
L-Glutamine is a “conditionally” essential amino acid. The average healthy person can usually make enough glutamine to meet biological needs. A shortage of glutamine may arise when there is disease, injury or other physiological abnormality that increases the body’s requirement for glutamine. Glutamine is essential for the metabolism, structure, and function of the gastrointestinal tract and its associated immune component.* Glutamine serves as a major source of fuel for the cells that line the intestinal tract, helping to maintain their normal, healthy function.* Immune cells require glutamine to help function properly. During times of physical stress and disease i.e. lifting weights, cancer, severe burns, an individual’s requirement for glutamine increases dramatically. Providing the body with glutamine as L-glutamine helps maintain lean muscle mass, helps the healing process and supports the body during all types of physical stress.*
Features:
Our L-glutamine is the highest quality, pharmaceutical grade, free form L-glutamine available.
It comes in a convenient powdered form which makes it easy to take the higher doses required by many individuals.
Free form (predigested and ready to be used by the body) L-glutamine 5,000mg per scoop
Benefits:
L-glutamine is known as a conditionally-essential amino acid, meaning that the body is capable of making it, but in certain conditions and disease states, the body can’t make enough to meet biological requirements.
L-glutamine is the most abundant amino acid found in the blood and serves as a major source of fuel for the cells that line the intestinal tract.*
L-glutamine is essential for a normal, healthy immune system (of which about 1/3 resides in the GI tract) and during infection glutamine requirements increase.*
During trauma, glutamine requirements increase several-fold. If requirements are not met, the body will begin to breakdown muscle tissue (high glutamine content) as a source of glutamine. This is one of the reasons why severe trauma and or illness result in a significant loss of mean muscle mass and bodyweight.
Higher amounts of L-glutamine must be provided during trauma or illness in supplemental form, as it is difficult to get the necessary amounts through diet alone.
SUGGESTED USE: As a Dietary Supplement, adults take one scoop in eight ounces of water, one (1) to three (3) times daily, or as directed by a health care professional.
Ingredients
L-Leucine, L-Isoleucine, and L-Valine, commonly known as Branched Chain Amino Acids or BCAAs, cannot be produced by the body and must be consumed through diet or dietary supplements. They are essential to building and maintaining muscle tissue and have long been used by athletes and other active individuals to activate protein synthesis and reduce muscle breakdown caused by intense training or physical activity.Vegetarian BCAA 1,000 mg- Branch Chain Amino Acids with Glutamine and B VitaminsBCAA's and Glutamine are essential to building and maintaining muscle tissue.BCAA's activate protein synthesis and reduce muscle breakdown caused by intense training or physical activity.Glutamine is the most abundant building block of protein in the body. The body can make enough glutamine for its regular needs. But during times of extreme stress (i.e. after intense exercise or an injury), your body may need more glutamine than it can make. Glutamine plays a major role in helping your muscles repair themselves after stressPubChem notes that one of the main roles L-glutamine plays in muscle recovery is moving nitrogen atoms from wherever they are to where they are needed. To build muscle, you need to maintain a positive nitrogen balance. After a heavy workout, rushing nitrogen to your damaged muscles stimulates tissue repair. If glutamine is lacking in the body, the damaged tissue may stay damaged because it doesn't have the materials to rebuild.
Label
Experiencing fatigue during a tough workout or during a day of heat and humidity is our body signaling it may need more electrolytes to help maintain proper fluid balance. Maintaining a proper balance of electrolytes and proper hydration is critically important to our energy levels, as well as physical and mental endurance. Of equal importance: getting the right balance of vitamins, minerals, and herbs to support a healthy innate immune response. Staying hydrated is not only important for energy and focus but has us better prepared for illness should it arrive. ImmunoLYTE Fizz supports both energy and immune function with a tasty drink we can add to our water and enjoy throughout the day.†
Features
1200 mg Vitamin C, Vitamin D3 25 mcg (1000 IU) & Zinc 11 mg.
500 mg Proprietary Complex with Arabinogalactan (from Larix laricina) and Beta-Glucan (from Saccharomyces cerevisiae) to support immune function.†
75 mg Proprietary Herbal Immune Blend with Elderberry Fruit Extract, Ginger Root, Powder, Echinacea Powder, Garlic Bulb Extract for an extra immune boost.†
6 key Minerals (Calcium, Magnesium, Sodium, Potassium, Phosphorous, and Manganese) for electrolyte recovery.†
B-Complex plus Chromium for energy support.†
Also available in great-tasting orange flavor.
Free of major food allergens: Contains No sugar, dairy, wheat, gluten, eggs, peanuts, tree nuts, fish, shellfish, preservatives, artificial colors, or flavors.
Gluten Free, Non GMO and Vegan.
Benefits
Formulated with efficacious doses of vitamin C, vitamin D3 & zinc for immune support.†
A great-tasting way to support hydration for more consistent energy, endurance & recovery.†
During daily or distant travel, a convenient way to supplement the right balance of vitamins, minerals, and herbs in two delicious flavors.†
LABEL (BERRY)
LABEL (ORANGE)
The conjugated linoleic acids are a group of fatty acids with conjugated double bonds. These fatty acids occur naturally in edible fat, especially in beef and dairy products. Their presence in butter was first identified by Dr. Roland Booth in 1935. Dr. Booth also observed that the levels of these fatty acids in butter were much higher in the summer when the cows were eating grass rather than grain. As our diets change and we eat less meat and more low-fat and non-fat dairy products, our intake of CLA has decreased significantly. Two isomers of CLA are known to possess biological activity: cis-9, trans-11 and trans-10, cis 12. Each isomer has its own individual actions and there may also be synergistic effects from the two working together. Trans-10, cis 12 is the isomer that produces body composition changes by supporting the reduction of body fat.
Features:
High potency, 1,250 mg per soft gel
Contains 1,000 mg of active CLA
Optimal 1:1 ratio of isomers
Tested for heavy metals, microbial contamination and freshness
Easy to swallow soft gel
Benefits:
Helps modify body composition by supporting the reduction of body fat. *
Supports the reduction in body fat in part by helping to promote the reduction of lipid uptake by adipocytes (fat cells). *
Supports the inhibition of lipid synthesis by adipose tissue. *
Helps support lipolysis (breakdown of fats). *
Contributes to the support of healthy serum leptin levels; a hormone that regulates appetite. *
Supports a normal inflammatory response in animal studies. *
Demonstrated immune system modulating properties. *
LABEL
