Support cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation*

Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.*

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*

Benefits of Thorne’s Methyl-Guard Plus:

Nutritional support for individuals who have MTHFR gene mutations*
Enhanced cellular energy production fights fatigue*
Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*
Promotes fat metabolism and lean body composition*
Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*
Promotes liver detoxification of many substances, including hormones like estrogen*

Why is methylation important:

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

Cardiovascular health
Cellular energy production
Fat metabolism
Neurological function
DNA production
Liver detoxification processes
Eye health
Histamine balance

Who can benefit from Thorne's Methyl-Guard Plus:

Individuals with mutations to MTHFR and other genes that adversely affect methylation*
Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*
Women seeking support for estrogen metabolism and bone health*
Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*
Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Thorne's Methyl-Guard Plus:

Betaine, also known as trimethylglycine, is a superior methyl donor
The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*
Active forms of vitamins B2 and B6 – key cofactors in methylation processes
B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*
Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard^®

^{Suggested Usage:}

^{Take 1-3 capsules daily or as recommended by your health-care practitioner.}